Michail Antonio's goal in the second half was enough to give the Hummers all three points in a decisive match that could prove costly to Tottenham's top four chances.
"I think it’s the reality. First half was good for us. Second half they were better. They felt more energy than us and we conceded a lot of space for them to run into. We didn’t find a way to manage the ball properly," Pochettino said after the match.
"After Brighton everyone had a very good feeling, fantastic season and we’re arriving in a good way. Today the opposite way. We knew that to compete in the Premier League top four is very tough. First half we deserved it, second half they deserve it. It’s a little bit unfair the way we arrive in the competition but we can we do.?
Spurs remain third on the table with 70 points, three ahead of fourth-placed Chelsea who travel to Old Trafford on Sunday.